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YPO0773 YPO0773 irp1 irp1 YPO0776 YPO0776 irp2 irp2 YPO0777 YPO0777 YPO0774 YPO0774 YPO0778 YPO0778 YPO0775 YPO0775 irp5 irp5 YPO0625 YPO0625 YPO0772 YPO0772
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
YPO0773Putative thioesterase; Similar to Pseudomonas aeruginosa probable pyochelin biosynthetic protein PchC TR:AAG07617 (EMBL:AE004840) (251 aa) fasta scores: E(): 1.1e-30, 38.6% id in 236 aa, and to C-terminus of Streptomyces griseus probable cadicidin biosynthesis thioesterase SW:PABT_STRGR (P33586) (361 aa) fasta scores: E(): 6e-25, 36.4% id in 225 aa. (254 aa)    
Predicted Functional Partners:
irp1
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp1 TR:Q9Z373 (EMBL:AL031866) (3163 aa) fasta scores: E(): 0, 100.0% id in 3163 aa. Similar to Yersinia enterocolitica HMWP1 protein Irp1 TR:O54511 (EMBL:Y12527) (3161 aa) fasta scores: E(): 0, 97.9% id in 3163 aa.
 
 0.996
YPO0776
Putative siderophore biosysnthesis protein; Similar to N-terminus of Yersinia pestis yersiniabactin biogenesis protein Irp2 TR:Q9Z399 (EMBL:AL031866) (2041 aa) fasta scores: E(): 0, 31.1% id in 1659 aa, and to Pseudomonas aeruginosa pyochelin synthetase PchF TR:Q9RFM7 (EMBL:AF184622) (1809 aa) fasta scores: E(): 0, 34.1% id in 1957 aa. and to Vibrio anguillarum anguibactin biosynthesis protein AngR SW:ANGR_VIBAN (P19828) (1048 aa) fasta scores: E(): 0, 32.1% id in 844 aa. CDS contains a glutamine and threonine rich imperfect repeat region, residues 996 to 1065.
 
 
 0.995
irp2
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp2 TR:Q9Z399 (EMBL:AL031866) (2041 aa) fasta scores: E(): 0, 100.0% id in 2035 aa. Similar to Yersinia enterocolitica high-molecular-weight protein 2 Irp2 SW:HMP2_YEREN (P48633) (2035 aa) fasta scores: E(): 0, 98.6% id in 2035 aa. The previously sequenced Yersinia pestis Irp2 ORF starts at a valine situated 6 aa upstream from the methionine. However,the methionine start, has a good ribosome-binding site.
 
 
 0.980
YPO0777
Putative siderophore biosysnthesis protein; Similar to the C-terminus of Vibrio anguillarum anguibactin biosynthesis protein AngR SW:ANGR_VIBAN (P19828) (1048 aa) fasta scores: E(): 0, 40.7% id in 553 aa. N-terminus of the CDS is similar to an internal region of Yersinia pestis yersiniabactin biogenesis protein Irp2 TR:Q9Z399 (EMBL:AL031866) (2041 aa) fasta scores: E(): 0,45.1% id in 439 aa.
  
 0.956
YPO0774
Conserved hypothetical protein; Similar to Yersinia enterocolitica high-pathogenicity island protein Irp3 TR:O54512 (EMBL:Y12527) (365 aa) fasta scores: E(): 3.6e-30, 33.7% id in 362 aa, and to Yersinia pestis YbtU protein ybtU TR:Q9Z3C6 (EMBL:AL031866) (365 aa) fasta scores: E(): 3.6e-30, 33.8% id in 364 aa.
 
  
 0.946
YPO0778
Putative siderophore biosysnthesis protein; Similar to Yersinia pestis yersiniabactin biogenesis protein Irp2 TR:Q9Z399 (EMBL:AL031866) (2041 aa) fasta scores: E(): 0, 36.8% id in 2031 aa, and to C-terminus of Stigmatella aurantiaca myxothiazol biosynthetic protein MtaD TR:Q9RFK8 (EMBL:AF188287) (3291 aa) fasta scores: E(): 0, 32.0% id in 1435 aa.
 
  
 0.936
YPO0775
Conserved hypothetical protein; Similar to Corynebacterium diphtheriae DtxR/iron-regulated protein 2 Irp2 TR:Q46024 (EMBL:U02634) (369 aa) fasta scores: E(): 2.2e-06, 23.3% id in 339 aa. N-terminal region similar to N-terminus of Pseudomonas aeruginosa hypothetical protein PA4362 TR:AAG07750 (EMBL:AE004852) (352 aa) fasta scores: E(): 0.054, 27.8% id in 209 aa.
 
    0.929
irp5
Previously sequenced: Yersinia pestis yersiniabactin siderophore biosynthetic protein YbtE TR:Q56950 (EMBL:U50364) (525 aa) fasta scores: E(): 0, 100.0% id in 525 aa. Similar to Yersinia enterocolitica Irp5 protein TR:O54514 (EMBL:Y12527) (525 aa) fasta scores: E(): 0,97.9% id in 525 aa.
 
  
 0.871
YPO0625
Hypothetical protein; Similar to Paracoccus denitrificans hypothetical protein XoxI TR:Q51674 (EMBL:U34346) (183 aa) fasta scores: E(): 0.079, 27.0% id in 152 aa, and to Methylobacterium extorquens hypothetical protein MxaD TR:Q49142 (EMBL:L41608) (176 aa) fasta scores: E(): 0.14, 23.8% id in 147 aa. CDS DNA has a low G+C content, 34.67%. Possible horizontally acquired gene.
 
 
 0.862
YPO0772
Putative membrane protein; Similar to Yersinia enterocolitica,high-pathogenicity island, signal transducer protein Irp8 TR:Q9X9I7 (EMBL:AJ132668) (462 aa) fasta scores: E(): 3.9e-22, 27.9% id in 416 aa, and to Yersinia pestis protein hypothetical protein YbtX TR:Q9ZC28 (EMBL:AL031866) (462 aa) fasta scores: E(): 8e-22, 27.1% id in 421 aa.
 
    0.850
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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